Keyword: missense DSLP Strand: 9-10.C.3.3a Consider variability as a key component of informal inference by questioning whether observed differences are meaningful or not. e.g., phone battery lasts 6 hours one day and 4 the next—is this a real difference in battery life, or just normal variation from daily use
Uses 30 real variants from the BRCA Exchange to have students classify mutations by type (silent, missense, nonsense, frameshift, splice site), connect each to its protein...